Read-across for rat oral gavage repeated-dose toxicity for short-chain mono-alkylphenols: A case study

A 4-week Repeated Dose Toxicity Study of Glycine in Rats by Gavage Administration

In order to examine the toxicity profile of glycine, an authorized food additive, a solution of glycine in water for injection was administered orally (via gavage) to male SD rats (Crl:CD(SD)) once daily for 4 weeks at doses of 500, 1000 and 2000 mg/kg/day in a volume of 10 mL/kg. Control animals received vehicle only. No animals died, and no glycine-related changes were observed in body weight...

Sub-chronic Oral Toxicity Test Repeated Dose 90 - Day Oral Toxicity Study in Non-rodents

assessment of the effect of honey as a topical therapy for intra oral wound healing in rat.

چکیده ندارد.

Toxicity assessment of high fructose corn syrup-55: a repeated dose oral toxicity study in uterus and ovaries of female rats

Background: High-fructose corn syrup-55 (HFCS-55) is a common sweetener in the food industry. Recently, we have investigated and published the effects of uncontrolled long-term oral ingestion of 55-HFCS compared to sucrose on primary ovarian insufficiency in female rats. This study aimed to compare the effects of short-term controlled HFCS-55 administration with sucrose and its possible effects...

A 4-week Repeated dose Oral Toxicity Study of Mecasin in Sprague-Dawley Rats to Determine the Appropriate Doses for a 13-week, Repeated Toxicity Test

OBJECTIVES In this study, we investigated the 4-week repeated-dose oral toxicity of gami-jakyak gamcho buja decoction (Mecasin) to develop safe treatments. METHODS In order to investigate the 4-week oral toxicity of Mecasin, we administered Mecasin orally to rats. Sprague-Dawley (SD) rats were divided into four groups of five male and five female animals per group: group 1 being the control g...